{"id":9303,"date":"2025-03-12T12:08:48","date_gmt":"2025-03-12T12:08:48","guid":{"rendered":"https:\/\/palynziq.biomarin.com\/en-us\/?page_id=9303"},"modified":"2026-02-04T11:50:38","modified_gmt":"2026-02-04T11:50:38","slug":"about-pku","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/about-pku\/","title":{"rendered":"About PKU"},"content":{"rendered":"<div id=\"acf-block-67d9901718116\" class=\"wrapper hero-wrapper\">\n    <div class=\"hero hero-no-overlay\">\n                    <div class=\"hero-background-image hero-background-image-desktop\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/05\/about-pku-banner.png?v=1.39);\"><\/div>\n            <div class=\"hero-background-image hero-background-image-mobile\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/03\/header-image-half-final-e1745342080423.png?v=1.39);\"><\/div>\n                <div class=\"overlay\"><\/div>\n        <div class=\"wrapper\">\n            <div class=\"inner-wrapper\">\n                <div class=\"hero-content\">\n                                                                                    <h1>About PKU\n<\/h1>\n                                                                <p><strong>Managing PKU typically requires a diet that restricts food high in an amino acid called phenylalanine (Phe). However, most people struggle to control Phe levels with diet alone.<\/strong><\/p>\n                                                                            <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n    <\/div>\n\n<div id=\"acf-block-67d99017183ba\" class=\"block wrapped-content block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-67d99017185ae\" class=\"block-wysiwyg\">\n            <h3>High Phe levels can affect how you think, feel, and act<\/h3>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-67d18314b9cc3\" class=\"block split-content equal-bias block-zero-top block-zero-bottom\" data-muted-autoplay=\"false\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t                                                                <div class=\"content-block first-block\">\n                                                                                                <h4><span style=\"color: #000000\">People without PKU<\/span><\/h4>\n                                                                                                                                                                                                                                                                                                                    \n                                    \n                                    \n                                    \n                                    <figure>\n                                        <div class=\"image\">\n                                                                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/03\/people-without-pku.png?v=1.39\" alt=\"People without PKU have enough of the PAH enzyme to break down Phe so it doesn&#039;t build up in the blood.\" \/>                                                                                    <\/div>\n                                                                            <\/figure>\n                                                                                    <\/div>\n                    \n                                            <div class=\"content-block second-block\">\n                                                                                                <h4><span style=\"color: #000000\">People with PKU<\/span><\/h4>\n                                                                                                                                                                                                                                                                                                                    \n                                    \n                                    \n                                    \n                                    <figure>\n                                        <div class=\"image\">\n                                                                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/03\/people-with-pku.png?v=1.39\" alt=\"Poeple with PKU don&#039;t have enough of the PAH enzyme to break down Phe, so it builds up in the blood.\" \/>                                                                                    <\/div>\n                                                                            <\/figure>\n                                                                                    <\/div>\n                                                \t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-6807a0f7b21e3\" class=\"block wrapped-content\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<figure id=\"acf-block-6807a0f7b23eb\">\n    <div class=\"image image-responsive image-rounded image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/symptoms-desktop-1900x617.png\" alt=\"Forgetfullness, Anxiety, Depression, Brain fog, Difficulty focusing, irritability, moodiness\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/symptoms-mobile.png?v=1.39\" alt=\"\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-67d9a5c1bfe9a\" class=\"block call-to-action call-to-action-no-overlay block-tight-top block-tight-bottom\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2023\/10\/promo_background.jpg?v=1.39);\">\n\t\t\t\t<div class=\"overlay\"><\/div>\n\t\t\t\t<div class=\"cta-content\">\n\t\t\t\t                            <div class=\"cta-image\">\n                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2023\/10\/lightbulb_icon@2x-e1702403330886.png?v=1.39\" alt=\"\" \/>                        <\/div>\n                    \t\t\t\t\t<div class=\"cta-content-main\">\n                        <div class=\"content-block\">\n\t\t\t\t\t        \t\t\t\t\t        \t\t\t\t\t\t        <h2 class=\"h3\">Over time, the effects of high Phe add up. That&#8217;s why experts recommend lowering Phe levels to below 6 mg\/dL and keeping them that way.\n<\/h2>\n\t\t\t\t\t\t    \t\t\t\t\t\t    \t\t\t\t\t    <\/div>\n\t\t\t\t\t                        <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-67d9884c04e64\" class=\"block wrapped-content bg-band bg-band-white block-zero-top block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-67d19ccc202ab\" class=\"block-wysiwyg\">\n            <h3>Keeping Phe levels low can be hard.<\/h3>\n    <\/div>\n\n<figure id=\"acf-block-67d9884c05014\">\n    <div class=\"image image-responsive image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/About9outof10Chart-1.png?v=1.39\" alt=\"\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/About9outof10Chart-Mobile-copy-1.png?v=1.39\" alt=\"About 9 out of 10 adults struggle to keep their Phe levels low with diet alone\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-67d9884c04e64\" class=\"block wrapped-content bg-band bg-band-white block-zero-top block-zero-bottom\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<figure id=\"acf-block-67d9884c05014\">\n    <div class=\"image image-responsive image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/sarah-quote-1900x399.png\" alt=\"Dietary management is really hard because no one is perfect with their diet quote from Sarah\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2025\/04\/sarah-quote-mobile.png?v=1.39\" alt=\"\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-67d19a1eecc88\" class=\"block call-to-action block-tight-top\">\n    <div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\" style=\"\">\n\t\t\t\t<div class=\"overlay\"><\/div>\n\t\t\t\t<div class=\"cta-content\">\n\t\t\t\t    \t\t\t\t\t<div class=\"cta-content-main\">\n                        <div class=\"content-block\">\n\t\t\t\t\t        \t\t\t\t\t        \t\t\t\t\t\t        <h2 class=\"h3\">Adding PALYNZIQ to your PKU treatment plan can help keep Phe levels low.\n<\/h2>\n\t\t\t\t\t\t    \t\t\t\t\t\t    \t\t\t\t\t    <\/div>\n\t\t\t\t\t                                <div class=\"content-block\">\n                                <p><a class=\"button button-ghost button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/why-palynziq\/\" target=\"_self\">Learn how<\/a><\/p>\n                            <\/div>\n\t\t\t\t\t                        <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-9303","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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