{"id":6659,"date":"2023-10-12T23:05:48","date_gmt":"2023-10-12T23:05:48","guid":{"rendered":"https:\/\/palynziq.biomarin.com\/en-us\/?page_id=6659"},"modified":"2025-12-02T12:00:45","modified_gmt":"2025-12-02T12:00:45","slug":"see-the-results","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/see-the-results\/","title":{"rendered":"See the results"},"content":{"rendered":"
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Over time, the majority of people reached an expert-recommended Phe level\n<\/h1>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n <\/div>\n\n
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Before starting PALYNZIQ, people participating in the study had an average Phe level of 20 mg\/dL<\/strong>. In a study following 118 people with PKU:<\/p>\n <\/div>\n\n

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*21% of participants (25\/118) stopped taking PALYNZIQ before reaching a Phe level below or equal to 6 mg\/dL. Of those, 10 participants stopped treatment due to side effects. A total of 3% of participants (4\/118) did not reach a Phe level below or equal to 6 mg\/dL before completing the study.<\/p>\n<\/figcaption>\n <\/figure>\n <\/div>\n <\/div>\n<\/div>\n\n

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In fact, most people taking PALYNZIQ eventually reached a Phe level below or equal to 2 mg\/dL.\n<\/h2>\n\t\t\t\t\t\t \t\t\t\t\t\t \t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n
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\u2020<\/sup>24% of participants (28\/118) stopped taking PALYNZIQ before they reached a Phe level below or equal to 2 mg\/dL. Additionally, 11 participants did not reach a Phe level below or equal to 2 mg\/dL before completing the study.<\/p>\n

Reaching a Phe level below 0.5 mg\/dL is called HypoPhe. If your Phe level decreases below 0.5 mg\/dL while taking PALYNZIQ, your doctor may reduce your dose and\/or modify your diet to increase it.<\/p>\n<\/figcaption>\n <\/figure>\n <\/div>\n <\/div>\n<\/div>\n\n

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Real Talk:<\/em> A lower Phe level takes time<\/h2>\n

Hear firsthand from real adults with PKU about the process of lowering Phe levels.<\/p>\n <\/div>\n \t\t<\/div>\n\t<\/div>\n<\/div>\n\n

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Your clinic team will monitor your Phe levels and suggest any changes to your dose or diet to help you reach your goals.\n<\/h2>\n\t\t\t\t\t\t \t\t\t\t\t\t \t\t\t\t\t <\/div>\n\t\t\t\t\t <\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n
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Diet or no diet, you can start PALYNZIQ<\/h2>\n

Most people did NOT consume a Phe-restricted diet while taking PALYNZIQ.<\/strong><\/p>\n

A Phe-restricted diet is when people get more than 75% of their protein from medical food\/formula.<\/p>\n

A separate analysis of the 250 people taking PALYNZIQ during a clinical study found that*:<\/p>\n <\/div>\n\n

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were not on a Phe-restricted diet before starting PALYNZIQ.<\/strong><\/p>\n <\/div>\n<\/div>\n\n

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were not on a Phe-restricted diet at their last assessment at the end of the study.<\/strong><\/p>\n <\/div>\n<\/div>\n\n

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*40% of patients (101\/250) were taking no medical protein before starting. About 91% (92\/101) of them still did not take any medical protein at their last assessment.
\n<\/small>43% (108\/250) were taking some form of medical protein before starting. About 48% (52\/108) of them still did so at their last assessment.
\n<\/small>16% (41\/250) got more than 75% of their protein from medical food\/formula before starting. About 29% (12\/41) still did so at their last assessment.<\/small><\/small><\/p>\n <\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n <\/div>\n <\/div>\n<\/div>\n\n

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Stay in the loop with news and updates about PALYNZIQ\n<\/h4>\n \n \n <\/div>\n
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Connect with us<\/a><\/p>\n <\/div>\n<\/div>\n\n

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Learn about insurance coverage and more\n<\/h4>\n \n \n <\/div>\n
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Find support<\/a><\/p>\n <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-6659","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nSee the results - BioMarin Palynziq Patient EN-US<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/see-the-results\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"See the results - BioMarin Palynziq Patient EN-US\" \/>\n<meta property=\"og:url\" content=\"https:\/\/palynziq.biomarin.com\/en-us\/see-the-results\/\" \/>\n<meta property=\"og:site_name\" content=\"BioMarin Palynziq Patient EN-US\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-02T12:00:45+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/palynziq.biomarin.com\/en-us\/see-the-results\/\",\"url\":\"https:\/\/palynziq.biomarin.com\/en-us\/see-the-results\/\",\"name\":\"See the results - 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