{"id":10880,"date":"2026-02-03T14:31:08","date_gmt":"2026-02-03T14:31:08","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10880"},"modified":"2026-04-23T15:41:14","modified_gmt":"2026-04-23T15:41:14","slug":"teens","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/teens\/","title":{"rendered":"Results with teens"},"content":{"rendered":"<div id=\"acf-block-69832e876b38f\" class=\"block url-tabs bg-band block-zero-top block-zero-bottom block-remove-bottom-padding bg-band-light-green\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h1>PALYNZIQ study results<\/h1>\n            \n                                                                                                <ul class=\"tabs\">\n                                                                                            <li class=\"white\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/adults\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-adults.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Adults<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                                                            <li class=\"green\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/teens\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-teens.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Teens<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                    <\/ul>\n                                                        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69832e876b74c\" class=\"block wrapped-content bg-band bg-band-alternative block-zero-top block-zero-bottom\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/doodle-1024x519.png);\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69832e876b8e8\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Over time, teens achieved lower Phe\u2014below expert-recommended levels<\/h2>\n<p style=\"text-align: center\">In an ongoing study of teens ages 12\u201317 with PKU, initial Phe levels averaged about 17 mg\/dL.<\/p>\n    <\/div>\n\n<div id=\"acf-block-69832e876bae4\" class=\"block boxed-content block-tight-bottom boxed-content-white-yellow\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t\t\t\t\t\n<div id=\"acf-block-69832e876bb0e\" class=\"block-wysiwyg\">\n            <p style=\"text-align: center\"><strong>Exploratory data from the ongoing study<\/strong><\/p>\n<p style=\"text-align: center\">By a data cutoff in October 2025, most teens* had taken PALYNZIQ injection\u2028for an average of 28 months, and:<\/p>\n    <\/div>\n\n<figure id=\"acf-block-69832e876c06e\">\n    <div class=\"image image-responsive image-natural-size image-align-center\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/teens-lower-phe-graph-e1774548323277.png?v=1.50\" alt=\"Chart showing that 25% of teens reach Phe levels below 6 mg\/dL by 7 months, 50% by 10 months, and 75% by 15 months\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/04\/teens-callout-mob-2.svg\" alt=\"\" \/>\t\t\t<\/div>\n            <\/div>\n            <figcaption><p>This was an exploratory outcome from the clinical trial. Results may vary. Please talk to your healthcare provider if you have any questions.<\/p>\n<\/figcaption>\n    <\/figure>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-699ed9020ad71\" class=\"block-wysiwyg\">\n            <p><small>*This only includes teens in the study who were originally randomized to take PALYNZIQ.<br \/>\n<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-699edc331ac96\" class=\"block wrapped-content bg-band bg-band-tertiary block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-699edbe7e3641\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background left-align popout-quote bg-white\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/D-jace-camera-1.png?v=1.50\" alt=\"Jace taking PALYNZIQ on his travels\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                        <div class=\"quote-block\">\n                                <p>I definitely feel more confident, because I feel more in charge of my life.<\/p>\n                            <\/div>\n                                                                            <p class=\"cite\">\u2014Jace<\/p> \n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-stories\/#jace-holly\" class=\"button button-arrow\" target=\"\">See Jace&#039;s story<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69832e876b74c\" class=\"block wrapped-content bg-band bg-band-alternative block-zero-top block-zero-bottom\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/doodle-1024x519.png);\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69832e876b8e8\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Many teens reached even lower Phe levels\u2014similar to those without PKU.<\/h2>\n<p style=\"text-align: center\">Nearly half (17\/36) of teens taking PALYNZIQ had a Phe level below or equal 2 mg\/dL.<\/p>\n    <\/div>\n\n<div id=\"acf-block-69832e876bae4\" class=\"block boxed-content block-zero-top block-tight-bottom boxed-content-white-yellow\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t                    <div class=\"heading-wrap\">\n                                                <h3>Once PALYNZIQ works, results continue\n<\/h3>\n                                            <\/div>\n                \t\t\t\t\n<div id=\"acf-block-69832e876bb0e\" class=\"block-wysiwyg\">\n            <p style=\"text-align: center\">For those who achieved at least one Phe level of 10 mg\/dL:<\/p>\n<p>&nbsp;<\/p>\n    <\/div>\n\n<figure id=\"acf-block-69832e876c06e\">\n    <div class=\"image image-responsive image-natural-size image-align-center\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/D-7-out-of-10-teens-graphic-1.svg\" alt=\"Nearly 7 out of 10 teens (17\/25) were able to reach a Phe level below or equal to 2 mg\/dL.\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/M-7-out-of-10-teens-graphic-1.svg\" alt=\"Nearly 7 out of 10 teens (17\/25) were able to reach a Phe level below or equal to 2 mg\/dL.\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32b5c3\" class=\"block cards cards-2-col bg-band block-zero-top block-zero-bottom\" style=\"\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-698215a32bc07\" class=\"card card-fixed-button card-centered bg-light-purple card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-faqs-1.svg\" alt=\"\" \/>                \n                                                                                                            <p>Answers to common questions about PALYNZIQ can help you to learn more.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/faqs\/\" target=\"_self\">See the FAQs<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32bc9c\" class=\"card card-fixed-button card-centered bg-cyan-blue card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/peer-connect-logo-1.svg\" alt=\"PALYNZIQ peer connect logo\" \/>                \n                                                                                                            <p>Get matched with someone taking PALYNZIQ who has walked in your shoes.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                          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