{"id":10878,"date":"2026-02-03T14:30:00","date_gmt":"2026-02-03T14:30:00","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10878"},"modified":"2026-04-07T11:06:48","modified_gmt":"2026-04-07T11:06:48","slug":"adults","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/adults\/","title":{"rendered":"Results with adults"},"content":{"rendered":"<div id=\"acf-block-69820a237f173\" class=\"block url-tabs bg-band block-zero-top block-zero-bottom block-remove-bottom-padding bg-band-light-purple\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h1>PALYNZIQ study results<\/h1>\n            \n                                                                                                <ul class=\"tabs\">\n                                                                                            <li class=\"purple\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/adults\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-adults.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Adults<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                                                            <li class=\"white\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/teens\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-teens.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Teens<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                    <\/ul>\n                                                        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69820a237f447\" class=\"block wrapped-content bg-band bg-band-secondary block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-69820a237f652\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Over time, adults achieved lower Phe\u2014below expert-recommended levels.<\/h2>\n<p style=\"text-align: center\">Before starting PALYNZIQ, people participating in the study had an average Phe level of 20 mg\/dL.<\/p>\n    <\/div>\n\n<div id=\"acf-block-69820a237f8a5\" class=\"block boxed-content boxed-content-white-yellow\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t                    <div class=\"heading-wrap\">\n                                                <h3>In 118 people taking PALYNZIQ in the study:\n<\/h3>\n                                            <\/div>\n                \t\t\t\t\n<div id=\"acf-block-699ee97e9d413\" class=\"image-text-block content-align-center block-zero-top\">\n            <div class=\"image-block medium\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/three-of-four.svg\" alt=\"\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <h3>3 out of 4 people <span class=\"alt\">(89\/118) had a\u2028Phe level<\/span> below or equal to 6 mg\/dL<span class=\"alt\">.<sup>*<\/sup><\/span>\n<\/h3>\n                            <\/div>\n<\/div>\n\n<figure id=\"acf-block-699ed322c3b8c\">\n    <div class=\"image image-responsive image-rounded image-natural-size image-align-center\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/adults-chart-phe-level.png?v=1.50\" alt=\"Timeline showing adults Phe levels over 6, 10 ,15 months\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/adult-time-efficacy-mob.svg\" alt=\"Timeline showing adults Phe levels over 6, 10 ,15 months\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n<div id=\"acf-block-699ed322c3d88\" class=\"pal-rounded-cta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"cta-container\">\n                                <div class=\"cta-icon\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/icon_consistency-2-e1772462163894.png?v=1.50\" alt=\"\" \/>                <\/div>\n                \n                                <div class=\"cta-content\">\n                    <p style=\"text-align: center\"><span class=\"alt\"><strong>THE POWER OF CONSISTENCY<\/strong><\/span><\/p>\n<p style=\"text-align: center\">Over time, people who stuck with PALYNZIQ were able to reach their treatment goals.<\/p>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6982165333d3d\" class=\"block-wysiwyg\">\n            <p><small>*21% (25\/118) of patients stopped taking PALYNZIQ before reaching a Phe level below or equal to 6 mg\/dL. Of those, 10 patients stopped due to side effects. 3% (4\/118) did not reach a Phe level equal to or below 6 mg\/dL before completing the study.<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32ad8e\" class=\"block wrapped-content bg-band bg-band-tertiary block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-698215a32b080\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background left-align popout-quote bg-white\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/m-damon-dj-1-e1772016527691.png?v=1.50\" alt=\"Damon being a DJ and taking PALYNZIQ\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                        <div class=\"quote-block\">\n                                <p>I\u2019m really excited about being able to focus on the things that I desire in life.<\/p>\n                            <\/div>\n                                                                            <p class=\"cite\">\u2014Damon<\/p> \n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-stories\/\" class=\"button button-arrow\" target=\"\">Watch PALYNZIQ stories<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32b0dc\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-698215a32b0fe\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">Most people reached even lower Phe levels\u2014similar to those without PKU.<\/h2>\n    <\/div>\n\n<div id=\"acf-block-698215a32b142\" class=\"block boxed-content boxed-content-white-yellow\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t                    <div class=\"heading-wrap\">\n                                                <h3>In 118 people taking PALYNZIQ in the study:\n<\/h3>\n                                            <\/div>\n                \t\t\t\t\n<div id=\"acf-block-699ee97e9d413\" class=\"image-text-block content-align-center block-zero-top block-zero-bottom\">\n            <div class=\"image-block medium\">\n            <figure>\n                <div class=\"image image-rounded\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/two-of-three.svg\" alt=\"\" \/>                <\/div>\n            <\/figure>\n        <\/div>\n        <div class=\"content-block\">\n                    <h3>More than <span class=\"alt\">2 out of 3<\/span> people (79\/118) had a\u2028Phe level <span class=\"alt\">below or equal to 2 mg\/dL<\/span>.<sup>\u2020<\/sup>\n<\/h3>\n                            <p><strong>Reaching a Phe level below 0.5 mg\/dL is called HypoPhe<\/strong>. If your Phe levels reach HypoPhe while taking PALYNZIQ, your clinic team may reduce your dose and\/or modify your diet to increase them.<\/p>\n                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32b162\" class=\"block-wysiwyg\">\n            <p><small><sup>\u2020<\/sup>24% (28\/118) of patients stopped taking PALYNZIQ before they reached a Phe level below or equal to 2 mg\/dL. Additionally, 11 patients did not reach a Phe level below or equal to 2 mg\/dL before completing the study.<\/small><\/p>\n    <\/div>\n\n\n<div id=\"acf-block-698215a32b331\" class=\"popout-cta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"cta-container\">\n                                    <div class=\"popout-eyebrow\">\n                        <p>Did you know?<\/p>\n\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/Lightbulb-Icon.png?v=1.50\" alt=\"\" \/>                                            <\/div>\n                \n                                <div class=\"cta-content\">\n                    <p style=\"text-align: center\"><span class=\"alt\">PEOPLE WITHOUT PKU<\/span> have\u00a0Phe\u00a0levels between 0.5 and 2 mg\/dL.<\/p>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32b5c3\" class=\"block cards cards-2-col bg-band block-zero-top block-zero-bottom\" style=\"\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-698215a32bc07\" class=\"card card-fixed-button card-centered bg-light-purple card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-faqs-1.svg\" alt=\"\" \/>                \n                                                                                                            <p>Answers to common questions about PALYNZIQ can help you to learn more.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/faqs\/\" target=\"_self\">See the FAQs<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-698215a32bc9c\" class=\"card card-fixed-button card-centered bg-cyan-blue card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/peer-connect-logo-1.svg\" alt=\"PALYNZIQ peer connect logo\" \/>                \n                                                                                                            <p>Get matched with someone taking PALYNZIQ who has walked in your shoes.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/peer-connect\/\" target=\"_self\">Sign up<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":10693,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-10878","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Results with adults - BioMarin Palynziq Patient EN-US<\/title>\n<meta name=\"description\" content=\"Over time, adults achieved lower Phe\u2014below expert-recommended levels. Before starting PALYNZIQ, people participating in the study had an average Phe level of 20 mg\/dL.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/adults\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adult Study Results\" \/>\n<meta property=\"og:description\" content=\"Over time, adults achieved lower Phe\u2014below expert-recommended levels. 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