{"id":10805,"date":"2026-01-28T16:36:23","date_gmt":"2026-01-28T16:36:23","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10805"},"modified":"2026-04-07T10:59:23","modified_gmt":"2026-04-07T10:59:23","slug":"adults","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/hidden-impact-of-pku\/adults\/","title":{"rendered":"Hidden impact adults"},"content":{"rendered":"<div id=\"acf-block-697a3b07e2bc6\" class=\"block url-tabs bg-band block-zero-top block-zero-bottom block-remove-bottom-padding bg-band-light-purple\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h1>Understand the hidden impact of PKU<\/h1>\n            \n                                                                                                <ul class=\"tabs\">\n                                                                                            <li class=\"purple\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/hidden-impact-of-pku\/adults\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-adults.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Adults<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                                                            <li class=\"white\">\n                                                                        <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/hidden-impact-of-pku\/teens\/\">\n                                                                                                                <div class=\"tab-icon\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/icon-teens.png?v=1.50\" alt=\"\" \/>                                        <\/div>\n                                                                            <div class=\"tab-text\">\n                                            <span class=\"tab-header\">Teens<\/span>\n                                            <span class=\"tab-subtitle\"><\/span>\n                                        <\/div>\n                                    <\/a>\n                                <\/li>\n                                                                                    <\/ul>\n                                                        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-697a3bf4ce76f\" class=\"block wrapped-content bg-band bg-band-secondary block-zero-top block-zero-bottom\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/background-pattern.png?v=1.50);\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-697a3bf4ce8d7\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">For adults, balancing work, time with family and friends, and a restricted diet isn\u2019t easy.<\/h2>\n<p style=\"text-align: center\">If you struggle to maintain a restricted diet, you\u2019re not alone.<\/p>\n    <\/div>\n\n<figure id=\"acf-block-69a8243bbf37e\">\n    <div class=\"image image-responsive image-rounded image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/Card.svg\" alt=\"About 9 out of 10 adults struggle to keep their Phe levels low with diet alone\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/Card-4.png?v=1.50\" alt=\"About 9 out of 10 adults struggle to keep their Phe levels low with diet alone\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6980c8950a717\" class=\"block wrapped-content\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6980c8950aa46\" class=\"icon-list-block three-cols\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h3>When people are unable to follow a restricted diet over the long term, Phe levels increase.<\/h3>\n            \n                            <p class=\"subhead\"><strong>High Phe levels can lead to:<\/strong><\/p>\n            \n                        <ul>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/forgetfulness.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Forgetfulness<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/irritability.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Irritability<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/moodiness.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Moodiness<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/difficulty-focusing.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Difficulty focusing<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/cloudy.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Anxiety or depression\u00a0<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/brain-fog.png?v=1.50\" alt=\"\" \/>                        \n                                                    <p>Brain fog\u00a0\u00a0<\/p>\n                                            <\/li>\n                            <\/ul>\n                    <\/div>\n    <\/div>\n<\/div>\n\n\n<div id=\"acf-block-69a05d400dd4f\" class=\"pal-rounded-cta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"cta-container\">\n                                <div class=\"cta-icon\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-low-phe.svg?v=1.50\" alt=\"\" \/>                <\/div>\n                \n                                <div class=\"cta-content\">\n                    <p>Over time, the effects of high\u00a0Phe\u00a0add up. That\u2019s\u00a0why experts recommend lowering Phe\u00a0levels to below\u00a06 mg\/dL and keeping them that way.\u00a0<\/p>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6980caeab53df\" class=\"block wrapped-content bg-band bg-band-secondary-light block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6980caeab56cb\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background right-align bg-purple\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/1.1.1-damon-finding-flow.png?v=1.50\" alt=\"Damon being a DJ whilst on PALYNZIQ\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                                                <h3>PALYNZIQ can make a difference for adults with PKU<\/h3>\n                                                                            <p>Find out how PALYNZIQ can help lower Phe levels without requiring a restricted diet.<\/p>\n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/adults\/\" class=\"button button-arrow button-ghost\" target=\"\">See the results for adults taking PALYNZIQ<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6980caeab5727\" class=\"block wrapped-content bg-band bg-band-tertiary block-zero-top\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6980caeab577e\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background left-align popout-quote bg-white\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/D-kelsey-playing.png?v=1.50\" alt=\"Kelsey playing cards whilst on PALYNZIQ\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                        <div class=\"quote-block\">\n                                <p>Before PALYNZIQ, high Phe levels were a struggle\u2014I had a lot of brain fog and was struggling\u00a0to do basic tasks even on a day-to-day basis.<\/p>\n                            <\/div>\n                                                                            <p class=\"cite\">\u2014Kelsey<\/p> \n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-stories\/#kelsey\" class=\"button button-arrow\" target=\"\">See Kelsey&#039;s story<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":10685,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-10805","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - 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