{"id":10701,"date":"2026-01-20T16:06:49","date_gmt":"2026-01-20T16:06:49","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10701"},"modified":"2026-04-24T10:05:26","modified_gmt":"2026-04-24T10:05:26","slug":"dosing","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/dosing\/","title":{"rendered":"How to Take PALYNZIQ"},"content":{"rendered":"<div id=\"acf-block-698af8539851c\" class=\"hero pal-hero bg-blue\">\n    <div class=\"hero-container\">\n        <div class=\"wrapper\">\n                            <div class=\"hero-background-image hero-background-image-desktop\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/04\/dsk-find-a-clinic-header.png?v=1.51);\"><\/div>\n                <div class=\"hero-background-image hero-background-image-mobile\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/mob-find-a-clinic-header.png?v=1.51);\"><\/div>\n            \n                            <div class=\"attribution-tab\">\n                    <div class=\"attribution-image\">\n                        <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/LEO-nametag.svg?v=1.51\" alt=\"LEO-nametag\" \/>                    <\/div>\n\n                    <p>Finding his rhythm and taking PALYNZIQ<\/p>\n                <\/div>\n            \n            <div class=\"inner-wrapper\">\n                                    <div class=\"text-wrapper\">\n                                            <h1>PALYNZIQ puts you in control of your treatment routine<\/h1>\n                    \n                                            <p>The first injection will be under the supervision of a healthcare provider. After that, you\u2019ll start by self-injecting PALYNZIQ once a week. Then, your clinic team will adjust your dose based on how you respond to treatment. Your PALYNZIQ dose will be increased slowly so your body can get used to it.<\/p>\n                    \n                                        <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6992f99f5d8a2\" class=\"anchor-navigation\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <nav class=\"anchor-links\">\n                    <div class=\"down-arrow\"><\/div>\n                                                                        <div class=\"anchor-link\">\n                                <a href=\"#palynziq-dosage\" target=\"\"><p>PALYNZIQ Dosage<\/p>\n<\/a>\n                            <\/div>\n                                                                                                <div class=\"anchor-link\">\n                                <a href=\"#videos-to-support-you\" target=\"\"><p>Videos to Support You<\/p>\n<\/a>\n                            <\/div>\n                                                                                                <div class=\"anchor-link\">\n                                <a href=\"#tips-to-stay-on-track\" target=\"\"><p>Tips to Stay on Track<\/p>\n<\/a>\n                            <\/div>\n                                                            <\/nav>\n\n                <nav class=\"mobile-anchor-links\">\n                    <div class=\"down-arrow\"><\/div>\n                    <div class=\"form-item\">\n                        <label for=\"anchor-links-mobile\">Jump to:<\/label>\n                        <select class=\"text\" id=\"anchor-links-mobile\" name=\"anchor-links-mobile\">\n                            <option value=\"#\">Jump to:<\/option>\n                                                                                                <option value=\"#palynziq-dosage\"><p>PALYNZIQ Dosage<\/p>\n<\/option>\n                                                                                                                                <option value=\"#videos-to-support-you\"><p>Videos to Support You<\/p>\n<\/option>\n                                                                                                                                <option value=\"#tips-to-stay-on-track\"><p>Tips to Stay on Track<\/p>\n<\/option>\n                                                                                    <\/select>\n                    <\/div>\n                <\/nav>\n                    <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"palynziq-dosage\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom block-remove-bottom-padding\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6981d5657945a\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">PALYNZIQ is taken at home on a daily basis<\/h2>\n    <\/div>\n\n<div id=\"acf-block-6981d5657957d\" class=\"block boxed-content block-tight-top boxed-content-white\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t\t\t\t\t\n<div id=\"acf-block-6981d56579592\" class=\"block-wysiwyg\">\n            <h3 style=\"text-align: center\">PALYNZIQ comes in prefilled syringes in 3 dosage strengths:<\/h3>\n    <\/div>\n\n<figure id=\"acf-block-6981d707c02e2\">\n    <div class=\"image image-responsive image-align-left\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/syringes-diagram.svg\" alt=\"syringes-diagram\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/Frame-143727606-1.svg\" alt=\"\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-6981e563b0aa2\" class=\"block boxed-content boxed-content-white info-box yellow-header\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box\">\n                                <div class=\"left-col\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/Skin-Graphic-1.svg?v=1.51\" alt=\"\" \/>                <\/div>\n                                <div class=\"right-col\">\n                                            <h3>PALYNZIQ is smaller than a flu shot<\/h3>\n                    \n                                            <p>The PALYNZIQ needle is small and thin\u2014it\u2019s just <strong>half an inch long<\/strong>. It is injected right under the skin (subcutaneously). This can make it less painful than a flu shot, which is injected into your muscle.<\/p>\n                    \n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"palynziq-dosage\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom block-remove-top-padding\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n\n<div id=\"acf-block-6981d707c03cd\" class=\"popout-cta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"cta-container\">\n                                    <div class=\"popout-eyebrow\">\n                        <p>Did you know?<\/p>\n\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/Lightbulb-Icon.png?v=1.51\" alt=\"\" \/>                                            <\/div>\n                \n                                <div class=\"cta-content\">\n                    <p>Your highest dose may not be the dose you stay on. YOUR CLINIC TEAM WILL MONITOR YOUR PHE LEVELS and may decrease your PALYNZIQ dose.<\/p>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-696778c8cc019\" class=\"block wrapped-content bg-band bg-band-tertiary block-zero-top block-zero-bottom block-remove-top-padding\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6968dd23a1c83\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background left-align popout-quote bg-white\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/leo-showing-strong-1.png?v=1.51\" alt=\"\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                        <div class=\"quote-block\">\n                                <p>I try to find ways to be more efficient and more mindful and make sure that I&#8217;m dosing correctly.<\/p>\n                            <\/div>\n                                                                            <p class=\"cite\">\u2014Leo<\/p> \n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-stories\/\" class=\"button button-arrow\" target=\"\">Watch PALYNZIQ stories<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"videos-to-support-you\" class=\"block video-grid pal-video-grid block-zero-top\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h2>Videos to support you on your PALYNZIQ journey<\/h2>\n                    <\/div>\n        <div class=\"video-grid-wrapper\">\n                                    <div class=\"pal-video-card\">\n                <div class=\"video-grid-thumbnail video-poster\">\n                                                                        <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/708610491\" style=\"\"><img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/th-step-guide.png?v=1.51\" alt=\"Woman explaining the process\" \/><\/a>\n                                                            <\/div>\n                <div class=\"video-grid-text\">\n                    <div class=\"text-inner\">\n                                                    <p class=\"video-title\">A step-by-step guide on how to inject PALYNZIQ\u00a0<\/strong><\/p>\n                        \n                                                    <p>Learn about injecting and administering PALYNZIQ with this step-by-step video.\n<\/p>\n                        \n                                                    <p class=\"video-duration\">16:12<\/p>\n                                            <\/div>\n                <\/div>\n            <\/div>\n                                    <div class=\"pal-video-card\">\n                <div class=\"video-grid-thumbnail video-poster\">\n                                                                        <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/664693742\" style=\"\"><img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/th-needle-fear.png?v=1.51\" alt=\"Cartoon of doctor injecting patient\" \/><\/a>\n                                                            <\/div>\n                <div class=\"video-grid-text\">\n                    <div class=\"text-inner\">\n                                                    <p class=\"video-title\">Overcoming the fear of needles\u00a0<\/strong><\/p>\n                        \n                                                    <p>Get comfortable with needles and injections with an overview of the education and support you\u2019ll receive with PALYNZIQ.\n<\/p>\n                        \n                                                    <p class=\"video-duration\">09:33<\/p>\n                                            <\/div>\n                <\/div>\n            <\/div>\n                                    <div class=\"pal-video-card\">\n                <div class=\"video-grid-thumbnail video-poster\">\n                                                                        <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/713565078\" style=\"\"><img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/th-doctor-explains.png?v=1.51\" alt=\"Cartoon depiction of doctor explaining to patient\" \/><\/a>\n                                                            <\/div>\n                <div class=\"video-grid-text\">\n                    <div class=\"text-inner\">\n                                                    <p class=\"video-title\">Anaphylaxis\u00a0explained\u00a0<\/strong><\/p>\n                        \n                                                    <p>Learn more about the potential risk of a severe allergic reaction with PALYNZIQ injection.\n<\/p>\n                        \n                                                    <p class=\"video-duration\">10:35<\/p>\n                                            <\/div>\n                <\/div>\n            <\/div>\n                                    <div class=\"pal-video-card\">\n                <div class=\"video-grid-thumbnail video-poster\">\n                                                                        <a class=\"modal-video permitted\" href=\"https:\/\/player.vimeo.com\/video\/1185566850\" style=\"\"><img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/04\/immunogenicity-thumbnail-1024x574.png\" alt=\"\" \/><\/a>\n                                                            <\/div>\n                <div class=\"video-grid-text\">\n                    <div class=\"text-inner\">\n                                                    <p class=\"video-title\">Responding to PALYNZIQ Therapy<\/strong><\/p>\n                        \n                                                    <p>Learn how the immune system responds to PALYNZIQ and how you\u2019ll be supported as you work toward lowering your Phe levels.\n<\/p>\n                        \n                                                    <p class=\"video-duration\">11:42<\/p>\n                                            <\/div>\n                <\/div>\n            <\/div>\n                    <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"tips-to-stay-on-track\" class=\"icon-list-block one-col\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                            <h3>Here\u2019s\u00a0how you can stay on track with your PALYNZIQ treatment plan<\/h3>\n            \n            \n                        <ul>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/blood-phe-levels-1.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>TRACK<\/strong><\/span> your Phe levels with regular testing.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-calendar-1.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>KEEP<\/strong><\/span> all your appointments with the clinic team.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-medications.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>TAKE<\/strong><\/span> all your medicines as prescribed by your healthcare provider.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-diet.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>FOLLOW<\/strong><\/span> a consistent diet.\u00a0Don\u2019t\u00a0make changes unless your clinic team tells you to do so.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-yield.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>REPORT<\/strong><\/span> any side effects to your clinic team right away.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/light-bulb.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>KNOW<\/strong><\/span> what signs to watch for and what to do if anaphylaxis occurs.<\/p>\n                                            <\/li>\n                                    <li>\n                                                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-epipen-nasal-spray.svg?v=1.51\" alt=\"\" \/>                        \n                                                    <p><span class=\"alt\"><strong>CARRY<\/strong><\/span> your\u00a0epinephrine device at all times during treatment with PALYNZIQ.<\/p>\n                                            <\/li>\n                            <\/ul>\n                    <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-69b1a91f71998\" class=\"block wrapped-content bg-band block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6981d7c7e2711\" class=\"block cards cards-2-col bg-band block-zero-top block-zero-bottom\" style=\"\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-6981d7c7e2b03\" class=\"card card-fixed-button card-centered bg-purple card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/peer-connect-logo-1.svg\" alt=\"PALYNZIQ peer connect logo\" \/>                \n                                                                                                            <p>Get matched with someone taking PALYNZIQ who has walked in your shoes.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/peer-connect\/\" target=\"_self\">Sign up<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-6981d7c7e2b62\" class=\"card card-fixed-button card-centered bg-cyan-blue card-inner-image card-inner-image-medium\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/care-team-e1771495893488.png?v=1.51\" alt=\"\" \/>                \n                                                                                                            <p>The right clinic team can help you on your PALYNZIQ journey.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/find-a-clinic\/\" target=\"_self\">Find a clinic near you<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-10701","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>How to Take PALYNZIQ - BioMarin Palynziq Patient EN-US<\/title>\n<meta name=\"description\" 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