{"id":10695,"date":"2026-01-20T16:06:08","date_gmt":"2026-01-20T16:06:08","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10695"},"modified":"2026-04-07T11:11:09","modified_gmt":"2026-04-07T11:11:09","slug":"diet-flexibility","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/diet-flexibility\/","title":{"rendered":"PALYNZIQ and Diet Flexibility"},"content":{"rendered":"<div id=\"acf-block-699edf55a3eea\" class=\"hero pal-hero bg-white\">\n    <div class=\"hero-container\">\n        <div class=\"wrapper\">\n                            <div class=\"hero-background-image hero-background-image-desktop\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/2.4-PALYNZIQ-and-diet-flexibility-Desktop-Header.png?v=1.47);\"><\/div>\n                <div class=\"hero-background-image hero-background-image-mobile\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/Mobile-Header.png?v=1.47);\"><\/div>\n            \n                            <div class=\"attribution-tab\">\n                    <div class=\"attribution-image\">\n                        <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/KELSEY-nametag.svg?v=1.47\" alt=\"\" \/>                    <\/div>\n\n                    <p>Playing to win<\/br> and taking PALYNZIQ<\/p>\n                <\/div>\n            \n            <div class=\"inner-wrapper\">\n                                    <div class=\"text-wrapper\">\n                                            <h1>Diet or no diet\u2014you can start PALYNZIQ<\/h1>\n                    \n                                            <p>PALYNZIQ is the first and only PKU treatment proven to lower Phe levels without requiring a restricted diet.<\/p>\n                    \n                                        <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-699edf55a421b\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/01\/background-pattern.png?v=1.47);\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-699edf55a43af\" class=\"block-wysiwyg\">\n            <h2 style=\"text-align: center\">In the clinical study, most people did NOT consume a Phe-restricted diet while taking PALYNZIQ<\/h2>\n<p style=\"text-align: center\">A Phe-restricted diet is when people get over 75% of protein intake from medical food.<\/p>\n    <\/div>\n\n<div id=\"acf-block-69a02894ded76\" class=\"block boxed-content block-tight-top block-zero-bottom boxed-content-white-yellow\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"box\">\n\t\t\t\t                    <div class=\"heading-wrap\">\n                                                <h3>A separate analysis of the 250 adults taking PALYNZIQ during the clinical study* found that:\n<\/h3>\n                                            <\/div>\n                \t\t\t\t\n<figure id=\"acf-block-69a02894defaa\">\n    <div class=\"image image-responsive image-natural-size image-align-center\">\n                    <div class=\"image-desktop\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/d-two-charts-phe-1.svg\" alt=\"84% were not on a Phe restricted diet before starting PALYNZIQ. 94% were not at their last assessment\" \/>\t\t\t<\/div>\n\t\t\t<div class=\"image-mobile\">\n\t\t\t    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/m-two-charts-phe.svg\" alt=\"84% were not on a Phe restricted diet before starting PALYNZIQ. 94% were not at their last assessment\" \/>\t\t\t<\/div>\n            <\/div>\n    <\/figure>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-69a57004bc590\" class=\"block-wysiwyg\">\n            <p>&nbsp;<\/p>\n<p><small>*A separate analysis of the results from the clinical trial (N=250) showed that:<\/small><\/p>\n<ul>\n<li><small>40% of adults (101\/250) were taking no medical protein before starting. Around 91% (92\/101) of them still did not take any medical protein at their last assessment.<\/small><\/li>\n<li><small>43% (108\/250) were taking some medical protein (less than or equal to 75% of protein from medical food\/formula). <\/small><small>Around 48% (52\/108) of them still did so at their last assessment.<\/small><\/li>\n<li><small>16% (41\/250) were getting more than 75% of their protein from medical food\/formula. Around 29% (12\/41) still did so at their last assessment.<\/small><\/li>\n<\/ul>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-6982031b82a49\" class=\"block wrapped-content bg-band block-zero-top block-zero-bottom\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-6982031b82aa2\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background right-align bg-purple\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/m-damon-dj-1-e1772016527691.png?v=1.47\" alt=\"Damon being a DJ and taking PALYNZIQ\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                                                <h3>Common questions about PALYNZIQ can guide conversations about treatment<\/h3>\n                                                                            <p>Find helpful questions and answers about PALYNZIQ to see if it could be right for you or your loved one.<\/p>\n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/faqs\/\" class=\"button button-arrow button-ghost\" target=\"\">Explore the FAQs<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-10695","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PALYNZIQ and Diet Flexibility - BioMarin Palynziq Patient EN-US<\/title>\n<meta name=\"description\" content=\"Diet or no diet\u2014you can start PALYNZIQ. It is is the first and only PKU treatment proven to lower Phe levels without requiring a restricted diet.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/diet-flexibility\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Diet and Flexibility\" \/>\n<meta property=\"og:description\" content=\"Diet or no diet\u2014you can start PALYNZIQ. 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