{"id":10689,"date":"2026-01-20T16:05:19","date_gmt":"2026-01-20T16:05:19","guid":{"rendered":"https:\/\/palynziqpatient-prod-001.azurewebsites.net\/en-us\/?page_id=10689"},"modified":"2026-04-07T11:00:58","modified_gmt":"2026-04-07T11:00:58","slug":"what-is-palynziq","status":"publish","type":"page","link":"https:\/\/palynziq.biomarin.com\/en-us\/what-is-palynziq\/","title":{"rendered":"What is PALYNZIQ"},"content":{"rendered":"<div id=\"acf-block-699ddbf03620f\" class=\"hero pal-hero bg-white\">\n    <div class=\"hero-container\">\n        <div class=\"wrapper\">\n                            <div class=\"hero-background-image hero-background-image-desktop\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/251212_AL_PALYNZIQ_D1_01_Look_017-2-6.png?v=1.47);\"><\/div>\n                <div class=\"hero-background-image hero-background-image-mobile\" style=\"background-image: url(https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/M-pal-works-differently.png?v=1.47);\"><\/div>\n            \n                            <div class=\"attribution-tab\">\n                    <div class=\"attribution-image\">\n                        <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/LEO-nametag.svg?v=1.47\" alt=\"LEO-nametag\" \/>                    <\/div>\n\n                    <p>Showing up strong  and taking PALYNZIQ<\/p>\n                <\/div>\n            \n            <div class=\"inner-wrapper\">\n                                    <div class=\"text-wrapper\">\n                                            <h1>PALYNZIQ WORKS DIFFERENTLY\u2014WITH SIGNIFICANT RESULTS<\/h1>\n                    \n                                            <p>PALYNZIQ is proven to be an effective long-term solution for lowering Phe levels.*<\/p>\n                    \n                                        <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-699ddbf03664c\" class=\"block cards cards-2-col bg-band bg-band-primary block-zero-top block-zero-bottom block-remove-bottom-padding\" style=\"\">\n\t<div class=\"wrapper\">\n\t\t<div class=\"inner-wrapper\">\n\t\t\t<div class=\"cards-title\">\n\t\t\t    \t\t\t\t    <h2>YOUR TREATMENT GOALS ARE FINALLY WITHIN REACH\u2014BECAUSE PALYNZIQ:\n<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"cards-wrapper\">\n\t\t\t    \n<div id=\"acf-block-699ddbf036db1\" class=\"card card-fixed-button card-centered bg-white card-inner-image card-inner-image-small\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/Layer_1.svg\" alt=\"\" \/>                \n                                                                                                            <p>Addresses the core of PKU (phenylketonuria) by directly substituting for the PAH enzyme that is missing or not working properly.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/how-palynziq-works\/\" target=\"_self\">See how it works<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-699ddbf036e4a\" class=\"card card-fixed-button card-centered bg-white card-inner-image card-inner-image-small\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-low-phe.svg\" alt=\"\" \/>                \n                                                                                                            <p>Lowers Phe below expert-recommended levels\u2028in both teens and adults.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/study-results\/\" target=\"_self\">View the study results<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-699dddaf08eec\" class=\"card card-fixed-button card-centered bg-white card-inner-image card-inner-image-small\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/icon-diet.svg\" alt=\"\" \/>                \n                                                                                                            <p>Does not require a restricted diet.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/diet-flexibility\/\" target=\"_self\">Learn about diet flexibility<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\n<div id=\"acf-block-699dddaf08f74\" class=\"card card-fixed-button card-centered bg-white card-inner-image card-inner-image-small\" data-muted-autoplay=\"false\">\n        <div class=\"card-content\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/support-care.svg\" alt=\"\" \/>                \n                                                                                                            <p>Provides ongoing support during your treatment through BioMarin.<\/p>\n                                                                                                                                                                                                                                                                        \n                                                                                        <\/div>\n                                <div class=\"card-actions\">\n                            \n                            <p><a class=\"button button-arrow\" href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-support\/\" target=\"_self\">Find help getting started<\/a><\/p>\n                                                                                    <\/div>\n<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n<\/div>\n\n<div id=\"acf-block-699dddaf091d2\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom block-remove-top-padding block-remove-bottom-padding\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-699dddaf093c6\" class=\"block-wysiwyg\">\n            <p><small>*Of the 77 adult patients who stayed in the clinical trial for at least 3 years, 66% (51\/77) had a Phe level \u22646 mg\/dL at year 3.<\/small><\/p>\n    <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-699f0ea112872\" class=\"block wrapped-content bg-band bg-band-primary block-zero-top block-zero-bottom block-remove-top-padding\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n\n<div id=\"acf-block-699ecaa59d3e6\" class=\"pal-rounded-cta\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"cta-container\">\n                                <div class=\"cta-icon\">\n                    <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/02\/light-bulb.svg?v=1.47\" alt=\"\" \/>                <\/div>\n                \n                                <div class=\"cta-content\">\n                    <p><span class=\"alt\">PALYNZIQ is backed by\u00a0nearly 2\u00a0decades of study.<\/span>\u00a0Since 2008, both clinical studies and many patients on treatment have shown\u00a0that\u00a0PALYNZIQ can help lower\u00a0Phe\u00a0levels.<\/p>\n                <\/div>\n                            <\/div>\n        <\/div>\n    <\/div>\n<\/div>\n        <\/div>\n    <\/div>\n<\/div>\n\n<div id=\"acf-block-699ecb2a219f4\" class=\"block wrapped-content bg-band bg-band-tertiary block-zero-top\" style=\"\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n                \n<div id=\"acf-block-699dddaf09850\" class=\"image-popout\">\n    <div class=\"wrapper\">\n        <div class=\"inner-wrapper\">\n            <div class=\"box-background left-align popout-quote bg-white\">\n                <div class=\"popout\">\n                                            <img decoding=\"async\" class=\"\" src=\"https:\/\/palynziq.biomarin.com\/en-us\/wp-content\/uploads\/sites\/3\/2026\/03\/kelsey-staying-focused-1.png?v=1.47\" alt=\"Kelsey focused sat with laptop\" \/>                                    <\/div>\n\n                <div class=\"content\">\n                                                                        <div class=\"quote-block\">\n                                <p>I considered PALYNZIQ because I couldn&#8217;t keep living with high Phe levels. I am extremely grateful for the fact that I made the decision to start. <\/p>\n                            <\/div>\n                                                                            <p class=\"cite\">\u2014Kelsey<\/p> \n                                            \n                                            <a href=\"https:\/\/palynziq.biomarin.com\/en-us\/patient-stories\/#real-talk\" class=\"button button-arrow\" target=\"\">See Kelsey&#039;s story<\/a>\n                                    <\/div>\n            <\/div>\n        <\/div>\n    <\/div>\n<\/div>  \n        <\/div>\n    <\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"class_list":["post-10689","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - 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